Preclinical MRI systems specifically designed for rodents molecular imaging studies, in-vivo and/or ex-vivo applications. The system is based on the revolutionary and advanced cryogen-free superconducting magnet technology. The system includes, 7.0 Tesla cryogen-free superconducting magnet (168 mm clear bore, 110 mm x 70 mm FOV, Integral R.F. shield), Shielded gradient coil set, MRS EVO spectrometer with two independent broadband RF transmit channels for excitation and decoupling, four independent broadband RF receive channels with a wide range of digital filters; 1000 Watt R.F. amplifier broadband 30MHz to 300 MHz; Preclinical User Software with Sequence library (ver 2.0BT), and rat and mouse volume and head RF coils, and imaging beds and InVicro MRI data analysis hardware and software. PIcture Credit – MR Solutions UK
In addition to high resolution anatomical imaging (T1/T2-W), MR Angiography, Susceptibility Weighted Imaging (SWI), T2* map, Resting State Functional MRI (rsfMRI), and Diffusion Tensor Imaging (DTI) are a few of the common modalities of MRI that we use.
Dr. Bose is the founder and the Director of this facility. Recently Dr. Bose was awarded an instrument grant that initiated the purchase of a PET ring to sequential PET/MRI imaging from rodents. This will provide an extraordinary capacity to scan whole body subjects. A PET scan can help to detect abnormal cellular activity following neurotrauma, and other diseases and to monitor how well treatment or rehabilitation therapies are working.
The Preclinical MRI/PET Facility is located on the third floor in the south west end of the Malcom Randall Main Hospital building, Room E359-1.